P001 Succinate, a gut microbiota-derived metabolite, modulates the inflammatory status of the creeping fat in Crohn’s disease
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چکیده
منابع مشابه
Changes in the composition and function of the gut microbiota in celiac disease
Evidence is supported the hypothesis that any changes in the composition and function of the gut microbiota play a fundamental role in a number of chronic inflammatory diseases including celiac disease (CD). In the last decade, several culture-independent methods have been developed to identify the components of the human microbiome. The study of microbiota based on nucleic acid analysis found ...
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The gut mucosal barrier plays an important role in maintaining a delicate immune homeostasis. The pathogenesis of inflammatory bowel disease (IBD) is considered to involve a defective mucosal immunity along with a genetic predisposition. Recent views have suggested an excessive response to components of the gut microbiota in IBD. A condition of "dysbiosis", with alterations of the gut microbial...
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15 صفحه اولThe gut microbiota in mouse models of inflammatory bowel disease
The intestine and the intestinal immune system have evolved through a symbiotic homeostasis under which a highly diverse microbial flora is maintained in the gastrointestinal tract while pathogenic bacteria are recognized and eliminated. Disruption of the balance between the immune system and the gut microbiota results in the development of multiple pathologies in humans. Inflammatory bowel dis...
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ژورنال
عنوان ژورنال: Journal of Crohn's and Colitis
سال: 2021
ISSN: 1873-9946,1876-4479
DOI: 10.1093/ecco-jcc/jjab076.130